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WELCOME TO BECK LAB

Understanding the complex biological systems using Big Data analysis

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"Torture the data, and it will confess to anything"

Ronald Coase

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RESEARCH

Big DATA Biology

The volume of cumulated biological data is growing exponentially.  We believe that the systematic profiling, reorganization and re-analyses of such large-scale available data can lead us to the whole new level of biological understanding.  The ultimate goal of our research is to understand complex biological systems and human diseases using integrative Big Data analyses and experimental validations.

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Gene Regulation at Transcription Level

Gene regulation is multi-layered complex process involving transcriptional and epigenetic regulations as well as chromosomal 3-D architectures.  We work to decipher the comprehensive biological mechanisms underlying gene regulation at the transcriptional level and how the dysregulation of such process is associated with human diseases, by using integrative data analyses.

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Chromatin Architecture in Aging

3-D chromatin architecture changes dynamically under a variety of conditions including cell fate determination, differentiation and development.  Disorganization of chromatin architecture is associated with various human diseases and is also a hallmark of aging.  We study how chromatin architecture changes give rise to the degenerative phenotype with age.

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PEOPLE

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Samuel Beck, Ph.D

Assistant Professor.  Boston University School of Medicine
Dermatology/Center for Aging Research

  • 2022-         Assistant Professor, Boston University School of Medicine

  • 2017-2022 Assistant Professor, MDI Biological Laboratory, ME

  • 2012-2017 Postdoc, The University of Texas at Austin. Systems Biology

  • 2011           Postdoc, Yonsei University, Network Biology

  • 2011           Ph.D., Seoul National University

  • 2004           B.S., Seoul National University

Email: sambeck [at] bu.edu

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Soojin Choi, Ph.D

Postdoctoral associate

  • 2023-         Postdoc.  Boston University School of Medicine

  • 2023           Ph.D., Yonsei University

Email: sjchoi [at] bu.edu

Vikas Kumar, Ph.D

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Postdoctoral associate

  • 2023-         Postdoc.  Boston University School of Medicine

  • 2022-2023 Principal Research Engineer at Linköping University, Sweden

  • 2018-2022 Associate Professor at Institute of Vertebrate Paleontology and Palaeanthropology, Beijing China

  • 2016-2018 Postdoc. Senckenberg, Biodiversity & climate research centre, Frankfurt, Germany

  • 2016           Ph.D., Goethe University, Frankfurt, Germany

Email: vikku19 [at] bu.edu

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Byung-Ju Kim, Ph.D

Postdoctoral Associate

  • 2024-present: Postdoc.  Boston University School of Medicine
    2022-2024: Research Professor, Convergence Research Center for Insect Vectors, Incheon University
    2019-2022: Research Associate, Human Genome Research Center, Incheon National University
    2014-2018: Assist Specialist, UC Berkeley
    2018: Ph.D., Integrated Omics for Biomedical Science, Yonsei University

Email: byungju [at] bu.edu

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Hyun-Jin Kim, B.Sc

Visiting Graduate Student

  • 2019-present: Ph.D. program, Chonnam National University

Email: hkim3 [at] bu.edu

Volunteer

  • Sedam Park (2023- ): Newton South high school

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Open position: Postdoctoral researcher

  • Fields of interest

    • Aging intervention study in mammalian system.​

    • Computational biology/Genomics

  • Please send the following materials to sambeck [at] bu.edu.​​

    • Cover letter briefly highlighting your experience and interests 

    • C.V.

    • Contact information of three references.

Open position: Undergraduate researcher

  • We are seeking passionate undergraduate students to join our team, dedicated to exploring the biology of aging and gene regulation via a combination of computational and experimental approaches.  Participants are expected to dedicate a minimum of 10 hours per week to this research project for at least one year.

Alumni

  • Postdoc​​

  • ​Visiting Scientist

    • ​HoonHee Seo (2023-2024): Currently an Assistant Professor at Soonchunhyang University

  • Rotation Student

    • Ali Gulhan (2024)

  • Undergraduate

    • Angelica Aguilar (2020): Currently a graduate student, The University of California, San Francisco

    • Elise A. Courtney (2020)​

    • Elliot Youth (2019): Currently in the MD/PhD program, The University of Chicago

    • Ezekiel Robinson (2019)

    • Romario Romain (2018): Currently a Research Assistant, Colorado State University

  • Research Assistant​

    • Ian Davis (2020-2022): Currently a Research Assistant, MDI Biological Laboratory​

    • Jessie Bolduc (2018-2020)

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Lab address: J-607, 609 Albany Street, Boston, Massachusetts 02118-2515
Phone: (617) 358-7631

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